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| Product Name | p53, Recombinant, Human |
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| Description | Purity ~94% (SDS-PAGE and Coomassie blue staining). p53 is expressed in a wide variety of tissues and plays a major role in preventing tumor development. It is involved in cell cycle regulation, functioning as a trans-activator to negatively regulate cell division by controlling a set of genes required for this process. It acts as a tumor suppressor in many tumor types by stimulating either apoptosis or growth arrest depending on the physiological circumstances and the cell type. Defects in p53 expression have been implicated in several diseases including; choroid plexus papilloma, lung cancer, head/neck squamous cell carcinomas, oesophageal squamous cell carcinoma, Li-Fraumeni syndrome, and hereditary adrenocortical carcinoma. Source: Recombinant corresponding to full length human p53, N-terminal c-Myc, 6His-tagged expressed in baculovirus in Sf21 insect cells. Molecular Weight: ~49kD |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | p53, Recombinant, Human (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53) |
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| Gene, Accession, CAS # | Accession: BC003596 |
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| Catalog # | 29572 |
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| Price | |
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| Order / More Info | p53, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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