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| Product Name | P300, Recombinant, Human, aa1046-1163, His-Tag |
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| Description | Purified (~78%). This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]. Source: Recombinant protein corresponding to aa1046-1163 from human bromodomain E1A binding protein p300, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~15.1kD Applications: Suitable for use in the study of bromodomain binding assays, screening inhibitors, and selectivity pro |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | P300, Recombinant, Human, aa1046-1163, His-Tag (E1A Binding Protein p300, EP300, KAT3B, RSTS2, E1A Binding Protein) |
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| Gene, Accession, CAS # | Accession: NM_001429, SwissProt: Q09472 |
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| Catalog # | 298437 |
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| Price | |
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| Order / More Info | P300, Recombinant, Human, aa1046-1163, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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