| 产品详情 |
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| Product Name | PKN1/PRK1, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). PKN1/PRK1 belongs to the protein kinase C superfamily which is activated by Rho family of small G proteins. PKN1/PRK1 is known to mediate the Rho-dependent signaling pathway and it can be activated by phospholipids and by limited proteolysis. PDPK1/PDK may also mediate insulin signals to the actin cytoskeleton and the proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggest its role in signal transduction related to apoptosis. PKN1/PRK signaling stimulates AR activity in the presence of adrenal androgens and in the presence of an AR antagonist. Source: Recombinant protein corresponding to human PKN1/PRK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~115kD Specific Activity: 30nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PKN1/PRK1, Recombinant, Human, GST-Tag (Protein Kinase N1, Serine/Threonine-protein Kinase N1, Protease-activated Kinase 1, PRK1, DBK, PKN1, PKN, MGC46204, PAK1, PRKCL1, PKC-L1) |
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| Gene, Accession, CAS # | Accession: BC040061 |
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| Catalog # | 500398 |
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| Order / More Info | PKN1/PRK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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