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| Product Name | PKN2, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). PKN2 (also known as PRK2) is a Rho effector and a member of the protein kinase C superfamily of serine/threonine kinases. PKN2 is an essential regulator of both entry into mitosis and exit from cytokinesis in HeLa S3 cells. PKN2 is required for abscission of the midbody at the end of the cell division cycle and for phosphorylation and activation of Cdc25B, the phosphatase required for activation of mitotic cyclin/Cdk1 complexes at the G2/M transition. C-terminal of PKN2 could be a potential drug target for effector-specific pharmacological intervention of Rho-medicated biological processes. Source: Recombinant protein corresponding to human PKN2/PRK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~145kD Specific Activity: 74nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PKN2, Recombinant, Human, GST-Tag (PRKCL2, PKN2, PRK2, PAK2, Pak-2, Serine/Threonine-protein Kinase N2, PRO2042, MGC71074, MGC150606) |
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| Gene, Accession, CAS # | Accession: NM_006256 |
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| Catalog # | 500399 |
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| Order / More Info | PKN2, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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