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| Product Name | IL2, Recombinant, Human (IL-2, T-Cell Growth Factor, TCGF, Interleukin-2) |
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| Description | Purity ~95% (SDS-PAGE). A helical bundle of 4 alpha-helices, IL2 is an immunoregulatory cytokine that is expressed by CD4+/CD8+ T cells, gamme-delta T cells, B cells, eosinophils and dendritic cells. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. While Human IL2 shares 56% and 66% amino acid sequence identity with mouse and rat IL2, respectively only human and mouse IL2 exhibit cross-species activity. Characteristically, IL2 exerts both autocrine and paracrine activity on T cells. In a regulatory role, IL2 is important for the development, survival, and function of regulatory T cells, it enhances Fas-mediated activation-induced cell death, and it inhibits the development of inflammatory Th17 cells. Recombinant Human IL2 is a non-glycosylated polypeptide that contains one intrachain disulfide bond. Source: Recombinant protein corresponding to human IL2 expressed in E. coli. Molecular Weight: ~15kD Biological Activi |
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| Size | 50ug, 100ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P60568 |
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| Catalog # | 500130 |
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| Order / More Info | IL2, Recombinant, Human (IL-2, T-Cell Growth Factor, TCGF, Interleukin-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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