| 产品详情 |
| Edit |   |
|---|
| Product Name | IL21, Recombinant, Human (IL-21, Za11, Interleukin-21) |
|---|
| Description | Purity ~95% (SDS-PAGE). IL-21 stimulates proliferation of B cell stimulated by crosslinking of the CD40 antigen. It inhibits proliferation stimulated by IL-4 plus anti-IgM. IL-21 augments stimulation of the proliferation of naive CD45RA(+) but not memory CD45R0(+) T cells mediated by engagement of CD3. IL-21 stimulates the proliferation of bone marrow progenitor cells and the expression of the natural killer cell marker CD56 in the presence of IL-15. The Interleukin-21 receptor is closely related to human IL-2 beta receptor. The receptor contains a WSXWS motif in the extracellular region, typical of type 1 cytokine receptors. The receptor is expressed on natural killer cells, T cells, and B cell line.The functional signaling complex activates Janus kinases JAK1, JAK3, and the STAT proteins STAT1, and STAT3. Source: Recombinant protein corresponding to human IL21 expressed in CHO cells. Molecular Weight: ~15kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of activated B Cells |
|---|
| Size | 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: Q9HBE4 |
|---|
| Catalog # | 500137 |
|---|
| Price | |
|---|
| Order / More Info | IL21, Recombinant, Human (IL-21, Za11, Interleukin-21) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|