| 产品详情 |
| Edit |   |
|---|
| Product Name | Pregnancy-Associated Plasma Protein A Fragment, Recombinant, Human |
|---|
| Description | Purity ≥ 95% by SDS-PAGE. Recombinant PAPP-A comprises a 191 amino acid fragment (81-271) corresponding to the PAPP-A `Jelly-Roll' domain fragment and is expressed in E. coli with an amino- terminal hexahistidine tag. PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems. Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500kD, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21). Applications: Suitable for use in ELISA. |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | P6000-81G |
|---|
| Price | |
|---|
| Order / More Info | Pregnancy-Associated Plasma Protein A Fragment, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|