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| Product Name | Factor IX, Human |
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| Description | Purity ≥95%. Human factor IX is prepared from fresh frozen plasma by a combination of conventional procedures and immunoaffinity chromatography (5). Purity is determined by SDS-PAGE analysis and activity is measured using a factor IX clotting assay. Human Factor IX is a glycoprotein which is synthesized in the liver (1-3). The domain structure of factor IX is similar to that of the other vitamin K dependent coagulation factors. The NH2-terminal region contains 12 g-carboxyglutamic acid (gla) residues which facilitate the calcium dependent binding of factor IX to negatively charged phospholipid surfaces. Two domains which are homologous to epidermal growth factor (EGF) span the region between the NH2-terminal gla domain and the activation peptide (Ala-146 to Arg-180). Factor IX is activated by either factor XIa or the factor VIIa/tissue factor/phospholipid complex. Cleavage at site A yields the intermediate IXa which is subsequently converted to the fully active form IXab by cleavage |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | F0017-15 |
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| Price | |
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| Order / More Info | Factor IX, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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