| 产品详情 |
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| Product Name | VEGFR2 Kinase Inhibitor VII, SKLB1002 |
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| Description | Purity ~98% (HPLC). A cell-permeable quinazoline that acts as a potent, ATP-binding site-targeting, VEGFR2-selective inhibitor (IC50=32nM), while exhibiting much reduced or little activity against 16 other kinases. An effective antiangiogenesis agent (98% inhibition of HUVEC tube formation at 10uM; 80% inhibition of zebrafish embryos intersegmental vessel growth at 2.5uM) that significantly suppresses SW620- and HepG2-derived tumor growth in mice (by 72% and 63%, respectively, in 18 days; 100mg/kg/day; i.p.) in vivo. Formula: C13H12N4O2S2 Molecular Weight: 320.4 Solubility: DMSO (2.5mg/ml) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | VEGFR2 Kinase Inhibitor VII, SKLB1002 (VEGFR Tyrosine Kinase Inhibitor XXXV, 6,7-Dimethoxy-4-(5-methyl-1,3,4-thiadiazol-2-ylthio)quinazoline, Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor VII) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217869 |
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| Order / More Info | VEGFR2 Kinase Inhibitor VII, SKLB1002 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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