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| Product Name | SHH, Recombinant, Human (HHG-1, Sonic Hedgehog) |
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| Description | Purity ~95% (SDS-PAGE). Highly conserved proteins, members of the Hedgehog family are widely represented throughout the animal kingdom. The three known mammalian Hedgehog proteins; Sonic (SHH), Desert (DHH) and Indian (IHH) hedgehog share a high degree of sequence and structural identity. SHH is specifically known to be expressed in fetal intestine, liver, lung and kidney. Recombinant Human SHH represents the N-product (N-terminal domain with Cys24 substituted by an Ile-Val-Ile sequence) which retains all the known signalling capabilities. Source: Recombinant protein corresponding to human SHH expressed in E. coli. Molecular Weight: ~20.1kD Biological Activity: Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.1-0.4ug/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 30ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q15465 |
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| Catalog # | 500447 |
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| Order / More Info | SHH, Recombinant, Human (HHG-1, Sonic Hedgehog) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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