| 产品详情 |
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| Antigenic Specificity | EMA / MUC1 |
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| Clone | S1D12D7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IHC, IHC-Fr, IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EMA / MUC1 Antibody (clone S1D12D7) LS-C202430. Specificity: S1D12D7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of S1D12D7 is GVTSAP as established with epitope fingerprinting. |
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| Immunogen | A MUC1 60mer tandem repeat NH2-(VTSAPDTRPAPGSTAPPAHG)3-COOH conjugated to bovine serum albumin. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability of the hybridomas was established by subcloning four times. |
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| Other Names | MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane |
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| Gene, Accession # | MUC1, Gene ID: 4582 |
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| Catalog # | LS-C202430 |
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| Price | |
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| Order / More Info | EMA / MUC1 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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