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Product Name | Interleukin 16 (IL16) (Active) protein |
Description | Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.ReferencesFeng M, et al. C16 peptide shown to prevent leukocyte infiltration and alleviate detrimental inflammation in acute allergic encephalomyelitis model.PMID: 23352465http://www.ncbi.nlm.nih.gov/pubmed/23352465Alternative Names: Pro-Interleukin-16, Interleukin-16, IL-16, Lymphocyte Chemoattractant Factor, LCF, IL16 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | IL16|LCF|NIL16|PRIL16|prIL-16|mKIAA4048|IL-16 |
Gene, Accession, CAS # | Gene ID: 3603 |
Catalog # | ABIN1096899 |
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Order / More Info | Interleukin 16 (IL16) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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