| 产品详情 |
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| Product Name | NQO1, Human, BioAssay™ ELISA Kit |
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| Description | NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector, both protects the cell from carcinogenic oxidative damage and stabilizes the tumor suppressor p53 protein. At high glycolysis levels NQO1 stabilizes and protects p53 from ubiquitin-independent degradation, a process that is NADH dependent, and also elevates NAD+/NADH levels. NAD+ and NADH play a crucial role in cellular energy metabolism, and a dysregulated NAD+/NADH ratio is implicated in metabolic syndrome. In humans, NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and liver dysfunction. Thus NQO1 may provide the basis for a new therapy for the treatment of metabolic syndrome. This assay is a sandwich ELISA for quantitative determination of human NQO1 in cells. A monoclonal antibody specific for NQO1 has been precoated onto the 96-well microtiter plate. Standards and samp |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NQO1, Human, BioAssay™ ELISA Kit (NAD(P)H Dehydrogenase [Quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione Reductase, NAD(P)H:quinone Oxidoreductase 1, Phylloquinone Reductase, Quinone Reductase 1, QR1, DIA4, NMOR1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N5379-52 |
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| Order / More Info | NQO1, Human, BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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