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| Product Name | CTLA4, Recombinant, Human, aa36-161, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). CTLA4 is a member of the immunoglobulin superfamily and transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Source: Recombinant protein corresponding to aa36-161 from human CTLA4 at N-terminal, fused to His-tag expressed in E. coli. Molecular Weight: ~15.9kD (149aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI D |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CTLA4, Recombinant, Human, aa36-161, His-Tag (Cytotoxic T-lymphocyte Protein 4 Isoform, CD, CD152, CELIAC3, GRD4, GSE, ICOS, IDDM12) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138640 |
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| Order / More Info | CTLA4, Recombinant, Human, aa36-161, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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