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| Product Name | GSS, Recombinant, Human (Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase) |
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| Description | Purity ~95% (SDS-PAGE). Glutathione synthetase, also known GSS, is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione. Defects in GSS are the cause of glutathione synthetase deficiency (GSS deficiency); also known as 5-oxoprolinuria or pyroglutamic aciduria. It is a severe form characterized by an increased rate of hemolysis and defective function of the central nervous system. Source: Recombinant corresponding to aa1-474 of human GSS protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHQH SSGLVPRGSH MATNWGSLLQ DKQQLEELAR QAVDRALAEG VLLRTSQEPT SSEVVSYAPF TLFPSLVPSA LLEQAYAVQM DFNLLVDAVS QNAAFLEQTL SSTIKQDDFT ARLFDIHKQV LKEGIAQTVF LGLNRSDYMF QRSADGSPAL KQIEINTISA SFGGLASRTP AVHRHVLSVL SKTKEAGKIL SNNPSKGLAL GIAKAWELYG SPNALVLLIA QEKERNIFDQRAIENELLAR NIHVIRRTFE DISEKGSLDQ DRRLFVDGQE IAVVYFRDGY MPRQYSLQNW EARLLLERSH AAKCPDIATQ LAGTKKVQQE LSRPGMLEML LPGQPEAVAR LRATF |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000169 |
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| Catalog # | G8136-15D |
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| Order / More Info | GSS, Recombinant, Human (Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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