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| Product Name | Protein Kinase Inhibitor H-89 |
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| Description | Purity ~90%. Protein Kinase Inhibitors The newly synthesized isoquinolinesulfonamide derivatives KN-62, KN-04, H-89, H-88, H-85, CKI-7, and CKI-8, as well as methoxybenzenesulfonamide derivatives KN-93 and KN-92 are protein kinase inhibitors which exert their strong inhibitory effects by directly binding to the protein kinase molecules. KN-62 is a selective and potent inhibitor of Ca++/calmodulin-dependent protein kinase II (Ca++/CaM Kinase II). The inhibition of KN-62 against Ca++/CaM Kinase II is more significant than the other protein kinases and is effective in lower concentrations. KN-04, which closely resembles KN-62 in its chemical structure, exhibits a weak protein kinase inhibition and is useful as a control for KN-62. KN-62 and KN-04 are useful tools for elucidation of the function of the enzyme in relation to cellular responses. H-89 and H-88 have a potent and selective inhibitory effect against cyclic AMP-dependent protein kinase (Protein Kinase A). H-89 is most powerful am |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Protein Kinase Inhibitor H-89 (PKI, N-(2-p-bromocinnamylaminoethyl]-5-isoquinolinesulfonamide) (N-(2-p-bromocinnamylaminoethyl]-5-isoquinolinesulfonamide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9104-35 |
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| Order / More Info | Protein Kinase Inhibitor H-89 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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