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Product Name | L-748,337 |
Description | Competitive β3-adrenoceptor antagonist that displays selectivity over β1 and β2 receptors (Ki values are 4.0, 204 and 390 nM for β3-, β2- and β1-adrenoceptors respectively). Inhibits cAMP accumulation in response to isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line. Purity 98%. MW (observed): 497.61 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[[3-[(2S)-2-Hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl]-acetamide |
Gene, Accession, CAS # | CAS: 244192-94-7 |
Catalog # | 2760/50 |
Price | |
Order / More Info | L-748,337 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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