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| Product Name | L-755,507 |
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| Description | Potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency 2-3-fold for large fragments and ~9-fold for point mutations, in human induced pluripotent stem cells (iPSCs). Purity 98%. MW (observed): 584.73 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 159182-43-1 |
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| Catalog # | 2197/10 |
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| Price | |
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| Order / More Info | L-755,507 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 18588298, 19281222, 21993887, 26429972 |
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| 产品资料 |
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