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Product Name | L-838,417 |
Description | Subtype-selective GABAA receptor partial agonist. Selectively binds to α1, α2, α3 and α5 subunits (Ki values are 0.79, 0.67, 0.67 and 2.25 nM respectively) but displays no efficacy at α1 (α1-sparing). Exhibits non-sedative anxiolytic, antinociceptive and anti-inflammatory activity in vivo. Purity 98%. MW (observed): 399.4 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine |
Gene, Accession, CAS # | CAS: 286456-42-6 |
Catalog # | 3250/10 |
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Order / More Info | L-838,417 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19940102, 30121248 |
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