| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Lys-63-specific deubiquitinase BRCC36 |
|---|
| Description | 2-316aa; Full Length. MW: 51.9kD. Purity >90% as determined by SDS-PAGE. Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it spec |
|---|
| Size | 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.2 mg (E-Coli), 0.05 mg (Baculovirus), 0.5 mg (E-Coli) |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [BR; CA1-A complex subunit BR; CC36BR; CA1/BR; CA2-containing complex subunit 3BR; CA1/BR; CA2-containing complex subunit 36; BRISC complex subunit BR; CC36] |
|---|
| Gene, Accession, CAS # | BRCC3, Gene ID: 79184, Accession: NP_001018065.1 |
|---|
| Catalog # | MBS950889 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Lys-63-specific deubiquitinase BRCC36 from MYBIOSOURCE INC. |
|---|
| Product Specific References | Isolation and sequence of two genes associated with a CpG island 5' of the factor VIII gene.Kenwrick S., Levinson B., Taylor S., Shapiro A., Gitschier J.Hum. Mol. Genet. 1:179-186(1992) The chromosomal translocation t(X;14)(q28;q11) in T-cell pro-lymphocytic leukaemia breaks within one gene and activates another.Fisch P., Forster A., Sherrington P.D., Dyer M.J.S., Rabbitts T.H.Oncogene 8:3271-3276(1993) Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like su |
|---|
| 产品资料 |
|
|