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| Product Name | UNC 1215 |
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| Description | Purity >98% by HPLC. Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC50 = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone |
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| Gene, Accession, CAS # | CAS: 1415800-43-9 |
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| Catalog # | LS-H2836 |
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| Order / More Info | UNC 1215 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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