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| Product Name | FK-866 |
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| Description | MW: 391.51. Purity ≥98% by NMR. Background: Cell-permeable. FK-866 is a highly specific non-competitive inhibitor of Nicotinamide phosphoribosyltransferase (NAMPT) (Ki = 0.4 nM), causing gradual NAD+ depletion. NAMPT functions as an intra-cellular and extra-cellular NAD biosynthetic enzyme that is important for regulating metabolism and stress resistance through sirtuins and other NAD-consuming regulators. NAD+ depletion by FK-866 directs delayed cell death by apoptosis in Hep-G2 human liver |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide] |
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| Gene, Accession, CAS # | CAS: 658084-64-1 |
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| Catalog # | MBS841941 |
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| Order / More Info | FK-866 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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