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| Product Name | CARD17, 1-110aa, Human, His tag, E Coli |
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| Description | MW: 14.3 kDa (133aa) confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. CARD17 is a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. This protein inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation. Recombinant human CARD17 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conv |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1.0 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Caspase recruitment domain-containing protein 17; Caspase recruitment domain family; member 17; INCA] |
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| Gene, Accession, CAS # | CARD17, Gene ID: 440068, Accession: NP_001007233 |
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| Catalog # | MBS204976 |
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| Order / More Info | CARD17, 1-110aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Lamkanfi M., et al. (2004), Biol. Chem. 279:51729-51738 |
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