| 产品详情 |
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| Product Name | LY2603618 |
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| Description | Purity >98%. LY2603618 is a checkpoint kinase 1 (Chk1) inhibitor (IC50 = 7 nM) that prevents the repair of DNA caused by DNA-damaging agents. It can inhibit Chk1 autophosphorylation and increase DNA damage-mediated Chk1 phosphorylation. LY2603618 has been used in xenograft tumor models to potentiate the antitumor efficacy of chemotherapeutic agents such as gemcitabine . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)-urea, IC-83, Rabusertib |
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| Gene, Accession, CAS # | CAS: 911222-45-2 |
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| Catalog # | LS-H8557 |
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| Price | |
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| Order / More Info | LY2603618 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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