| 产品详情 |
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| Product Name | Cdc2-Like Kinase Inhibitor IV, KH-CB19 |
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| Description | Purity ~95% (HPLC). A cell-permeable N-methylindolyl-enaminonitrile compound that acts as a potent, non-ATP mimetic binding and reversible inhibitor of Clk1 and Dyk1A (IC50=19.7 and 55.2nM, respectively) with moderate to excellent selectivity over Clk3 (IC50=530nM) and against 71-kinases. Shown to suppress phosphorylation of Ser/Arg-rich (SR) proteins, regulate alternative splicing and lower both full-length and alternatively spliced human tissue factor isoforms much more efficiently than Cdc2-Like Kinase Inhibitor, TG003 in HMEC-1 cells. Formula: C15H13Cl2N3O2 Molecular Weight: 338.2 Solubility: DMSO (50mg/ml) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cdc2-Like Kinase Inhibitor IV, KH-CB19 ((E)-Ethyl-3-(2-amino-1-cyanovinyl)-6,7-dichloro-1-methyl-1H-indole-2-carboxylate) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217260 |
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| Order / More Info | Cdc2-Like Kinase Inhibitor IV, KH-CB19 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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