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| Product Name | CDC25A, 1-524aa, Human, His tag, E Coli |
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| Description | MW: 63.2 kDa (560aa). Purity >80% by SDS-PAGE. M-phase inducer phosphatase 1, also known as CDC25A, is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact r |
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| Size | 0.01 mg, 0.05 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A; Cdc 25a; Cell division cycle 25 homolog A (S. pombe); Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform b; D9Ertd393e; EC 3.1.3.48; M phase inducer phosphatase 1; MGC115549] |
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| Gene, Accession, CAS # | CDC25A, Gene ID: 993, Accession: NP_001780 |
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| Catalog # | MBS203746 |
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| Order / More Info | CDC25A, 1-524aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Pereg Y., et al. (2010) Nat. Cell Biol. 12:400-406; Soerensen C.S., et al. (2003) Cancer Cell 3:247-258 |
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