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| Product Name | CDCA8, 19-280aa, Human, His tag, E Coli |
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| Description | MW: 31.6 kDa (283aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein may be required to direct the CPC to centromeric DNA. Deletion of CDCA8 delays mitotic progression and causes |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Cell division cycle-associated protein 8; Borealin; Dasra-B; PESCRG3] |
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| Gene, Accession, CAS # | CDCA8, Gene ID: 55143, Accession: NP_060571 |
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| Catalog # | MBS204057 |
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| Order / More Info | CDCA8, 19-280aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Gassmann R., et al. (2004) J Cell Biol.166:179-191.; Chang J L., et al. (2006) EXP Cell Res. 312:962-973. |
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