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| Product Name | Cdc42 Activation Assay |
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| Description | Background: Small GTP-binding proteins (or GTPases) are a family of proteins that serve as molecular regulators in signaling transduction pathways. Cdc42, a 21 kDa protein, belongs to the family of Rho GTPases regulates a variety of biological response pathways that include cell motility, cell division, gene transcription, and cell transformation. Like other small GTPases, Cdc42 regulates molecular events by cycling between an inactive GDP-bound form and an active GTP-bound form. In its active ( |
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| Size | 5 assays, 20 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168387 |
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| Order / More Info | Cdc42 Activation Assay from MYBIOSOURCE INC. |
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| Product Specific References | 1. Raftopoulou M., and Hall A. (2004) Dev Biol. 265: 23-32.2. Bar-Sagi D., and Hall A. (2000) Cell 103: 227-38.3. Benard, V., Bohl, B. P., and Bokoch, G. M. (1999) J. Biol. Chem. 274, 13198-13204.1. El-Sayed, F.G. et al. (2014). P2Y2 nucleotide receptor activation enhances the aggregation and self-organization of dispersed salivary epithelial cells. Am J Physiol Cell Physiol. 307: C83-C96.2. He, S. et al. (2013). SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility. J. Clin. Endocrinol. Metab. 98:E973-E980.3. Zhang, S. et al. (2008). The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating Cdc42 recruitment and activity. Cancer Res. 68:740-748.4. Somervaille, T. et al. (2006). Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell 10:257-268. |
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