| 产品名称 |
Profilin 2, Recombinant, Human (Profilin-2, Profilin II, Profilin-II, PFN2, PFN-2, D3S1319E, PFL) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Profilin 2, Recombinant, Human (Profilin-2, Profilin II, Profilin-II, PFN2, PFN-2, D3S1319E, PFL) |
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| Description | Purity ~ 95% (SDS-PAGE). Purified by using conventional chromatography techniques. PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the profilin family, PFN2 functions as an actin monomer-binding protein that influences the structure of the cytoskeleton by regulating actin polymerization in response to extracellular signals. At high concentrations, it prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Recombinant PFN2 protein, fused to His-tag at N-terminus, was expressed in E. coli. Source: Recombinant corresponding to aa1-140 of human PFN2 6x His tagged expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEG |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAH18049 |
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| Catalog # | P9005-89W |
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| Order / More Info | Profilin 2, Recombinant, Human (Profilin-2, Profilin II, Profilin-II, PFN2, PFN-2, D3S1319E, PFL) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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