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Antigenic Specificity | Bone Morphogenetic Protein 4 (BMP4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation . BMPs belongs to the TGF-beta superfamily, playing many diverse functions during development . BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems . BMP4 plays an essential role during development. Mouse embyros deficient in BMP4 die around the time of gastrulation . BMP4 regulates stem cell maintenance and differentiation in various systems . Synonyms: BMP2B, BMP2B1, MCOPS6, ZYME, |
Immunogen | Recombinant protein of human BMP4 |
Other Names | bmp-4|zbmp-4|zgc:100779|XBMP-4|bmp2b|bmp2b1|bmp4|ofc11|xbmp4|zyme|BMP4|bmp-2|bmp2|bmp2-4|cb670|zbmp-2|zbmp2|BMP2B|BMP2B1|MCOPS6|OFC11|ZYME|Bmp-4|Bmp2b|Bmp2b-1|Bmp2b1|BOMPR4A|BMP-4 |
Gene, Accession # | Gene ID: 652,12159,25296 |
Catalog # | ABIN1683411 |
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Order / More Info | Bone Morphogenetic Protein 4 (BMP4) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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