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| Product Name | VEGF , 121aa |
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| Description | Purity ~95% (SDS-PAGE). VEGF is a heavily glycosylated, homodimeric protein. The human factor occurs in several molecular variants of 121, 162, 145, 148, 165, 183, 189, 206aa, arising by alternative splicing of the mRNA. The splice forms of VEGF differ in biological properties such as the receptor types, which they recognize and their interaction with heparan sulfate proteoglycans. VEGF121 and VEGF165 are soluble secreted forms of the factor. The interaction of VEGF with heparin-like molecules of the extracellular matrix is required for efficient receptor binding. Protamine sulfate and suramin are capable of replacing the receptor-bound factor. This recombinant construct represents the isoform 121 of VEGFA. Source: Recombinant protein corresponding to human VEGF expressed in E. coli. Molecular Weight: ~14.3kD Biological Activity: The ED50 as determined by the dose-dependent proliferation of human umbilical vein endothelial cells (HUVEC) was found to be 10ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | VEGF (121aa), Recombinant, Human (Vascular Endothelial Growth Factor A, VEGF-A, Vascular Permeability Factor, VPF, VEGF-121aa, Vascular Endothelial Growth Factor 121aa (VEGFA) |
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| Gene, Accession, CAS # | SwissProt: P15693 |
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| Catalog # | 500534 |
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| Order / More Info | VEGF , 121aa from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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