产品名称 SMBA 1 from TOCRIS BIOSCIENCE
产品货号 5314/50
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 TOCRIS BIOSCIENCE
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Product NameSMBA 1
DescriptionHigh affinity and selective activator of Bax (Ki = 43.3 nM). Binds to the S184 binding pocket to block Bax phosphorylation. Does not bind to other Bcl-2 family members, including Bcl-2, Bak and Bid. Facilitates Bax insertion into the mitochondrial membrane and promotes Bax-dependent cytochrome c release. Induces apoptosis in lung cancer cell lines expressing high levels of Bax selectively over normal cells expressing low levels of Bax. Represses tumor growth of A549 lung cancer xenografts in mice. Purity 98%. MW (observed): 315.32
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol
Gene, Accession, CAS #CAS: 906440-37-7
Catalog #5314/50
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Order / More InfoSMBA 1 from TOCRIS BIOSCIENCE
Product Specific ReferencesPubMed: 25230299
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