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| Product Name | MED1, Recombinant, Human, aa878-1031, His-SUMO-Tag (Mediator of RNA Polymerase II Transcription Subunit 1) |
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| Description | Purity ~90% (SDS-PAGE). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Source: Recombinant protein corresponding to aa878-1031 from human MED1, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~32 |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Activator-recruited cofactor 205kD component, ARC205, Mediator complex subunit 1 Peroxisome proliferator-activated receptor-binding protein |
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| Gene, Accession, CAS # | SwissProt: Q15648 |
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| Catalog # | 374184 |
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| Order / More Info | MED1, Recombinant, Human, aa878-1031, His-SUMO-Tag (Mediator of RNA Polymerase II Transcription Subunit 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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