产品详情 |
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Product Name | NK 252 |
Description | Purity >98%. NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding site of Keap1. At 1.36 µM, it is reported to activate the NQO1-antioxidant response element in a luciferase reporter gene assay two-fold above background. NK 252 has been shown to downregulate the expression of fibrogenic genes, producing antifibrotic effects in a rat model of non-alcoholic steatohepatitis. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)-urea |
Gene, Accession, CAS # | CAS: 1414963-82-8 |
Catalog # | LS-H9017 |
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Order / More Info | NK 252 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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