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| Product Name | PTTG1, 1-202aa, Human, His tag, E Coli |
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| Description | MW: 24.1 kDa (222aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles; the first one is to help the transport of separase (cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Rec |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Pituitary tumor-transforming protein 1; EAP1; HPTTG; PTTG; TuTR1; SECuRIN; Pituitary tumor-transforming protein 1 ESP1 ASSOCIATED PROTEIN 1; Esp1-associated protein; MGC126883; MGC138276; Pds1; PTTG1 protein; PTTG1; Pituitary tumor transforming 1; PTTG 1; EAP 1; Cut2; Pituitary tumor transforming protein 1; AW555095; Pituitary tumor-transforming 1; isoform CRA_a; Pituitary tumor-transforming 1; isoform CRA_b; hPTTG; Pituitary tumor-transforming gene 1; TuTR 1; Pttg3; Pituitary tumor-transformin |
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| Gene, Accession, CAS # | PTTG1, Gene ID: 9232, Accession: NP_004210 |
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| Catalog # | MBS203367 |
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| Order / More Info | PTTG1, 1-202aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Chien W., et al. (2000) J Biol Chem. 275 (25):19422-7.; Tariq Hamid., et al. (2005) Molecular Cancer. 4 (1):3.; |
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