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| Product Name | PUMA, alpha, Human, Control Peptide (p53 Upregulated Modulator of Apoptosis) |
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| Description | Chromatographically purified. Synthetic peptide 17-aa, Human PUMA. Human control peptide sequence is also found in alternatively spliced PUMA-beta but not in gamma or delta forms. The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. P53 tumor-suppressor protein functions to inhibit the growth of tumor cells. Although p53 is not required for the growth and differentiation of normal cells, it may play a role in several cellular processes including senescence and differentiation. Mice lacking p53 show a high incidence of tumor formation. P53 inhibits cell growth through inactivation of both cell cycle arrest and apoptosis. Several p53-induces genes play a role in the induction of apoptosis. Through global profiling of genes that were expressed soon after p53 expression, a novel gene termed PUMA (p53-up |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9198-01A |
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| Order / More Info | PUMA, alpha, Human, Control Peptide (p53 Upregulated Modulator of Apoptosis) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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