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| Product Name | VEGF, Recombinant, Human, Animal Free (Vascular Endothelial Growth Factor121, VPF) |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant human VEGF121 is a 28.4kD disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains. Source: Recombinant protein corresponding to human VEGF expressed in E. coli Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4ng/ml. |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208711 |
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| Order / More Info | VEGF, Recombinant, Human, Animal Free (Vascular Endothelial Growth Factor121, VPF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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