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| Product Name | VEGF121, Recombinant, Human (Vascular Endothelial Growth Factor121, VPF) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. VEGF is a potent growth and angiogenic cytokine.It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability.Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis.VEGF signals through three receptors fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates.Recombinant human VEGF121 is a 28.4kD disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4ng/ml. AA Sequence: APMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRC |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143537 |
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| Order / More Info | VEGF121, Recombinant, Human (Vascular Endothelial Growth Factor121, VPF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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