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| Product Name | VEGF, Recombinant, Rat |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. VEGF is a potent growth and angiogenic cytokine.It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability.Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis.Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes.VEGF signals through the three receptors fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.Recombinant rat VEGF is a 38.5kD disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0-8.0ng/ml. AA Sequence: MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKP |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | VEGF, Recombinant, Rat (Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF165) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143536 |
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| Order / More Info | VEGF, Recombinant, Rat from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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