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| Product Name | IRAK1, Recombinant, Human, aa618-712, His-Tag |
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| Description | Purity ~95%. Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF). Source: Recombinant protein corresponding to human IRAK, fused to His-tag at C-terminal expressed in E.coli. Molecular Weight: ~15kD Applications: Suitable for use in ELISA and Western Blot. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IRAK1, Recombinant, Human, aa618-712, His-Tag (Interleukin-1 Receptor-associated Kinase 1, IRAK-1, IRAK) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149775 |
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| Order / More Info | IRAK1, Recombinant, Human, aa618-712, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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