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| Product Name | IRAK4, Recombinant, Human, GST-Tag (Interleukin-1 Receptor-Associated Kinase 4, IPD1, REN64, NY-REN-64) |
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| Description | Purified (~70-90%). Interleukin-1 receptor-associated kinase 4 (IRAK4) is an important mediator in the signal transduction of Toll-like receptor (TLR) and IL1R family members. IRAK4 is involved in the Toll-like receptor signaling pathway leading to Apoptosis. IRAK4 has molecular functions like protein binding, ATP binding, kinase activity and magnesium ion binding. Toll/IL-1 receptor family members like IRAK4 are central components of host defense mechanisms in a variety of species. One well conserved element in their signal transduction is the Ser/Thr kinase activity which couple early signaling events in a receptor complex at the plasma membrane to larger signalosomes in the cytosol. Source: Recombinant protein corresponding to human IRAK4, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~81kD Specific Activity: 435nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: BC013316, SwissProt: Q9NWZ3 |
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| Catalog # | 500185 |
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| Order / More Info | IRAK4, Recombinant, Human, GST-Tag (Interleukin-1 Receptor-Associated Kinase 4, IPD1, REN64, NY-REN-64) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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