| 产品详情 |
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| Product Name | IRAK2, Recombinant, Human, GST-Tag (Interleukin-1 Receptor-Associated Kinase 2, IRAK-2, MGC150550) |
| Description | Purified (~70-90%). Interleukin-1 receptor-associated kinase 2 (IRAK2) is important downstream signaling components of Toll-like receptors (TLRs). IRAKs were first described as signal transducers for IL-1 and later have been implicated in signal transduction of other members of the Toll/IL-1 receptor family. The interleukin-1 receptor (IL-1R) signaling pathway leads to NFB activation in mammals. To date, four mammalian IRAKs have been identified (IRAK-1, IRAK-2, IRAK-4, and IRAK-M). It is believed that IRAK-2 could be an additional therapeutic target for inhibiting IL-1-induced inflammation. Source: Recombinant protein corresponding to human IRAK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~103kD Specific Activity: 6nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
| Size | 10ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NM_001570 |
| Catalog # | 500184 |
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| Order / More Info | IRAK2, Recombinant, Human, GST-Tag (Interleukin-1 Receptor-Associated Kinase 2, IRAK-2, MGC150550) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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