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| Product Name | LAG-3,Fc, Recombinant, Mouse (Lymphocyte Activation Gene-3, FDC Protein, CD223) |
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| Description | Purity >95% (SDS-PAGE). Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. Biological Activity: Induces maturation of mouse dendritic cells in vitro. Induces CD4 and CD8 antigen-specific T cells responses when coinjected s.c. in mice, together with the antigen. Sequence: The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3). |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Lymphocyte Activation Gene-3, FDC Protein, CD223 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44994 |
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| Order / More Info | LAG-3,Fc, Recombinant, Mouse (Lymphocyte Activation Gene-3, FDC Protein, CD223) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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