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| Product Name | JW 67 |
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| Description | Inhibitor of canonical Wnt pathway signaling (IC50 = 1.17 μM); targets the β-catenin destruction complex (GSK-3β/AXIN/APC) to induce β-catenin degradation. Selective for the canonical Wnt pathway over the Sonic hedgehog (Shh) and NF-κB pathways. Blocks G1/S cell cycle progression in colorectal cancer (CRC) cell lines (GI50 = 7.8 μM). Purity 97%. MW (observed): 394.38 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Trispiro[3H-indole-3,2'-[1,3]dioxane-2'',3'''-[3H]indole]-2,2'''(1H,1'''H)-dione |
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| Gene, Accession, CAS # | CAS: 442644-28-2 |
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| Catalog # | 4651/50 |
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| Price | |
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| Order / More Info | JW 67 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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