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| Product Name | Streptopain, Recombinant, Streptococcus Pyogenes Serotype M28, aa146-398, His-SUMO-Tag (SpeB) |
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| Description | Purity ~90% (SDS-PAGE). Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Source: Recombinant protein corresponding to aa146-398 from streptococcus pyogenes serotype M28 speB, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~43.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Exotoxin type B SPE B Streptococcal cysteine proteinase, Streptococcus peptidase A, SPP |
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| Gene, Accession, CAS # | SwissProt: Q48R29 |
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| Catalog # | 375446 |
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| Order / More Info | Streptopain, Recombinant, Streptococcus Pyogenes Serotype M28, aa146-398, His-SUMO-Tag (SpeB) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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