| 产品详情 |
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| Product Name | Oxotremorine M (iodide) |
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| Description | A muscarinic acetylcholine receptor agonist and KCNQ2/3 potassium channel blocker; induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M2, M3 and M2/M3 knockout mice (EC50s = 0.36, 0.52, 1.62, and 1.48 µM, respectively); increases M4-induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC50 = 0.14 µM); inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M1 receptors and KCNQ2/3 potassium channels (IC50 = 1.1 µM); decreases KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 63939-65-1 mAChR-M KCNQ |
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| Gene, Accession, CAS # | CAS: 3854-04-4 |
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| Catalog # | 20847-50 |
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| Order / More Info | Oxotremorine M (iodide) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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