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| Product Name | Recombinant Human Docking protein 1 |
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| Description | 1-481aa; Full Length. MW: 68.4kD. Purity >90% as determined by SDS-PAGE. DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Downstream of tyrosine kinase 1; p62(dok); pp62 ] |
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| Gene, Accession, CAS # | DOK1, Gene ID: 1796, Accession: NP_001184189.1 |
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| Catalog # | MBS1368368 |
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| Order / More Info | Recombinant Human Docking protein 1 from MYBIOSOURCE INC. |
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| Product Specific References | p62(dok)a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells.Carpino N., Wisniewski D., Strife A., Marshak D., Kobayashi R., Stillman B., Clarkson B.Cell 88:197-204(1997) Molecular cloning of a truncated p62Dok1 isoform, p22Dokdel.Hubert P., Ferreira V., Debre P., Bismuth G.Eur. J. Immunogenet. 27:145-148(2000) Yu W., Sarginson J., Gibbs R.A. Generation and annotation of the DNA sequences of human chromosomes 2 and 4.Hillier L.W., Grav |
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