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| Product Name | IL15RA, BioAssay™ ELISA Kit (Mouse) (Interleukin 15 Receptor, alpha subunit) |
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| Description | Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor which is encoded by the gene IL15RA in humans. The human IL15RA gene was mapped to chromosome 10p15-p14 by FISH and the mouse Il15ra gene was mapped to chromosome 2. The cytoplasmic domain of IL15R-alpha, like that of IL2R-alpha, was dispensable for mitogenic signaling, suggesting that the primary role of the alpha chains is to confer high-affinity binding. At high concentrations, IL15, like IL2, was able to signal through a complex of IL2R-beta and -gamma in the absence of the alpha subunit. The soluble receptor displayed high affinity for IL15 and inhibited both binding of IL15 to the membrane receptor and IL15-induced cell proliferation. Sample Type: Cell culture supernates, serum and plasma (heparin, EDTA) Intended Use: For quantitative detection of mouse IL15RA in cell culture supernates, serum and plasma (heparin, EDTA). Sensitivity: <10pg/ml Range: 125-8000pg/ml Specificity: Natural and recombinan |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 16169, SwissProt: Q60819 |
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| Catalog # | 352934 |
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| Order / More Info | IL15RA, BioAssay™ ELISA Kit (Mouse) (Interleukin 15 Receptor, alpha subunit) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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