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| Product Name | Cell Cycle Checkpoint BioAssay™ Sample Kit (cdc2 (Tyr15), Chk1 (Ser345), Chk2 (Thr68), Rb (Ser795, Ser807/811), p53 (Ser15)) |
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| Description | Synthetic peptides (KLH coupled) corresponding to residues surrounding PhosphorylatedTyr15 of human cdc2; Phosphorylated Ser345 of human Chk1; Phosphorylated Thr68 of human Chk2; and Phosphorylated Ser795 and Phosphorylated Ser807/811 of human Rb. Mab is produced by immunizing mice with a synthetic Phosphorylated Ser15 peptide (KLH coupled) corresponding to residues surrounding Phosphorylated Ser15 of human p53. Recognizes cdc2 Phosphorylated (Tyr15), Chk1 Phosphorylated (Ser345), Chk2 Phosphorylated (Thr68), Rb Phosphorylated (Ser795, Ser807/811) and p53 Phosphorylated (Ser15). The cell-replication cycle demands great accuracy in order to avoid the accumulation of genetic damage. This process is controlled by molecular circuits called ``checkpoints'' that are common to all eukaryotic cells (1). Checkpoints monitor DNA integrity and cell growth prior to replication and division at the G1/S and G2/M transitions, respectively. The cdc2-cyclin B kinase is pivotal in regulating the G2/M tran |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_007194 |
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| Catalog # | C2612 |
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| Order / More Info | Cell Cycle Checkpoint BioAssay™ Sample Kit (cdc2 (Tyr15), Chk1 (Ser345), Chk2 (Thr68), Rb (Ser795, Ser807/811), p53 (Ser15)) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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