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| Product Name | Cell division cycle associated 8, Recombinant, Human, aa19-280, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein may be required to direct the CPC to centromeric DNA. Deletion of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach. Source: Recombinant corresponding to aa19-280 from human CDCA8, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MRKLASFLKD FDREVEIRIK QIESDRQNLL KEVDNLYNIE ILRLPKALRE MNWLDYFALG GNKQALEEAA TADLDITEIN KLTAEAIQTP LKSAKTRKVI QVDEMIVEEE EEEENERKNL QTARVKRCPP SKKRTQSIQG KGKGKRSSRA NTVTPAVGRL EVSMVKPTPG LTPRFDSRVF KTPGLRTPAA GERIYNISGN GSPLADSKEI FLTVPVGGGE SLRLLASDLQ RHSIAQLDPE ALGNIKKLSN RLAQICSSIR THK Molecular Weight: ~31.6kD (283aa) confirmed by MALDI-TOF |
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| Size | 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cell division cycle associated 8, Recombinant, Human, aa19-280, His-Tag (BOR, Borealin, BOREALIN, Cell division cycle-associated protein 8, Dasra-B, FLJ10468, FLJ12042, hDasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein) |
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| Gene, Accession, CAS # | Accession: NP_060571 |
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| Catalog # | C2098-69D |
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| Order / More Info | Cell division cycle associated 8, Recombinant, Human, aa19-280, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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